It is used in the synthesis of high efficient and low toxic pesticide monodimethamidine, dimethamidine, etc., as the reactive solvent and refined solvent of organic synthesis, widely used in medicine, dyes, spices, etc
The purpose is the important organic chemical raw materials and intermediates, which is a good organic solvent.
Used for the synthesis of highly effective and low toxicity single armour, double armour, etc.
It is used as an organic reaction solvent and solvent.
It is also widely used in medicine, dyes, spices and electrolysis, electroplating industry, etc.
Production method 1. Methylamine is produced by the reaction of methylamine and carbon monoxide.
Methyl formate is used by methyl formate and methylamine.
The reaction of ethyl formate and methylamine.
Will join the rest of the reactor ethyl formate, join methylamine solution under cooling, in 40 ℃ reflux reaction.
Then put the 3d in place, and the decompression of ethanol gets rougher.
The finished product is distilled by decompression.
The production method n-methylformamide has the following three synthetic processes.
(1) the method of methylamine
It's done by methylamine and carbon monoxide.
CO + CH3NH2 - HCONHCH3
A methylamine is 69.62% (mass fraction), methanol 29.87% (mass fraction) and 0.5% (mass fraction) of sodium methoxide one methylamine is 0.72% (for) a mixture of supply to the reactor of 87.05 kg/h, and at the same time supply content to 99.5% carbon monoxide 56.5 kg/h, the reaction temperature 90 ℃, pressure is 2.53 MPa.
Took an hour containing a mixture of methylamine 80.5% (mass fraction) of 140.75 kg, the N - methyl formamide generation, 113.4 kg per hour production capacity 1 l reactor for 1.89 kg per hour N - methyl formamide.
Methyl formate
The methyl formate reacts with the methyl amine.
CH3NH2 + HCOOCH3 - HCONHCH3 + CH3OH
The product is finished by the preliminary distillation and distillation, and the total yield is 90%.
The product content is 95% ~ 99.5%.
(3) ethyl formate
It's made up of ethyl formate and methylamine.
HCOOC2H5 + CH3NH2 - HCONHCH3 + C2H5OH
Adding ethyl formate reaction vessel first, and then join the methylamine solution under cooling [ethyl formate and aqueous methylamine press 1:1.2 (mol) ingredients], in 40 ℃ back mixing, and then placed in 3 d, reduced pressure recovery of ethanol, coarse product by vacuum distillation and finished products.
Class flammable liquid
Toxicity grade poisoning
Acute toxicity oral - rat LD50:4000 mg/kg;
Oral - mouse LD50:2600 mg/kg
Stimulate the data eye - 100 milligrams of rabbits
Inflammable hazard properties may be ignited by fire, high temperature, and strong oxidizing agents;
Combustion of toxic nitrogen oxide fumes
The packing features are fully packaged and lightly packed;
The reservoir is ventilated, far away from the open fire, the high temperature, the oxidizing agent, the acid is stored separately
Extinguishing agent foam, carbon dioxide, fog water, sand
Safety information
Danger mark T
The danger category is 61-21-r61-r21
Safety instructions 53-45-s53-s45
WGK Germany 1
RTECS LQ3000000 no.
TSCA Yes
PackingGroup II
Hazardous Substances Data 123-39-7 (Hazardous Substances Data)